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1

Advances in the directed metallation of azines and diazines (pyridines, pyrimidines, pyrazines, pyridazines, quinolines, benzodiazines and carbolines). Part 2: Metallation of pyrimidines, pyrazines, pyridazines and benzodiazines

Alain Turck, Nelly Plé, Florence Mongin, Guy Quéguiner

Journal:

Year:

2001

Language:

english

File:

PDF, 511 KB

english, 2001

2

Metalation of Pyrazinethiocarboxamides. Metalation of Diazines XXVI

Quéguiner, Guy, Fruit, Corinne, Turck, Alain, Plé, Nelly

Journal:

Year:

1999

Language:

english

File:

PDF, 477 KB

english, 1999

3

Use of sulfur derivatives as an ortho directing group for the metalation of diazines. Metalation of diazines. XVIII

Alain Turck, Nelly Plé, Paméla Pollet, Ljubica Mojovic, Jack Duflos, Guy Quéguiner

Journal:

Journal of Heterocyclic Chemistry

Year:

1997

File:

PDF, 547 KB

1997

4

Metalation of t-butyl sulfoxides, sulfones and sulfonamides of pyridazine and pyrazine. Metalation of diazines. XX

Alain Turck, Nelly Plé, Paméla Pollet, Guy Quéguiner

Journal:

Journal of Heterocyclic Chemistry

Year:

1998

File:

PDF, 628 KB

1998

5

Metalation of sulfoxides in the benzodiazine series. Diazines. Part 44

Nicolas Le Fur, Ljubica Mojovic, Nelly Plé, Alain Turck, Francis Marsais

Journal:

Year:

2005

Language:

english

File:

PDF, 298 KB

english, 2005

6

First Synthesis of a G-2 Melamine Dendrimer with Serinolic Peripheral Groups

Darabantu, Mircea, Pintea, Monica, Fazekas, Marijana, Lameiras, Pedro, Berghian, Camelia, Delhom, Isabelle, Silaghi-Dumitrescu, Ioan, Ple, Nelly, Turck, Alain

Journal:

Letters in Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 193 KB

english, 2006

7

ChemInform Abstract: Syntheses and Metalation of Pyridazinecarboxamides and Thiocarboxamides. Diazines. Part 32.

Corinne Fruit, Alain Turck, Nelly Ple, Ljubica Mojovic, Guy Queguiner

Journal:

Year:

2002

File:

PDF, 35 KB

2002

8

Synthesis and molecular design of 4,8-diaryl- and 4,8-di(arylethynyl)pyrido[4,3-d]pyrimidines: Potential applications in nonlinear optics. Diazines Part 49

Alexandrine Busch, Alain Turck, Nelly Plé

Journal:

Journal of Heterocyclic Chemistry

Year:

2008

Language:

english

File:

PDF, 549 KB

english, 2008

9

The proton sponge–triethylamine tris(hydrogen fluoride) system as a selective nucleophilic fluorinating reagent for chlorodiazines

Mircea Darabantu, Thierry Lequeux *, Jean-Claude Pommelet, Nelly Plé, Alain Turck, Loı̈c Toupet

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 186 KB

english, 2000

10

Organozinc Derivatives of Diazines, Metalation of Diazines XXIII

Quéguiner, Guy, Turck, Alain, Plé, Nelly, Leprêtre-Gaquere, Anne

Journal:

Year:

1998

Language:

english

File:

PDF, 232 KB

english, 1998

11

Metallation of Pyridin-2-yldiazines. Use of Pyridine Ring as ortho-Directing Group. Diazines. Part 45.

Camelia Berghian, Mircea Darabantu, Alain Turck, Nelly Ple

Journal:

Year:

2006

File:

PDF, 24 KB

2006

12

Syntheses in the Nitrogen π-Deficient Heterocycles Series Using a Barbier Type Reaction Under Sonication. Diazines. Part 29

Anne Leprêtre, Alain Turck, Nelly Plé, Guy Quéguiner

Journal:

Year:

2000

Language:

english

File:

PDF, 115 KB

english, 2000

13

Metalation of diazines XVII Very hindered bases as new metalating agents, Improvement of regioselectivity for the metalation of 3-chloro-6-methoxypyridazine

Ljubica Mojovic, Alain Turck, Nelly Plé, Muriel Dorsy, Bruno Ndzi, Guy Quéguiner

Journal:

Year:

1996

Language:

english

File:

PDF, 409 KB

english, 1996

14

Additions covalentes de nucléophiles sur les pyrido-as-triazines

Plé, Nelly, Turck, Alain, Queguiner, Guy

Journal:

Canadian Journal of Chemistry

Year:

1992

File:

PDF, 444 KB

1992

15

Metallation of pyridin-2-yldiazines. Use of pyridine ring as ortho-directing group. Diazines. Part 45

Camelia Berghian, Mircea Darabantu, Alain Turck, Nelly Plé

Journal:

Year:

2005

Language:

english

File:

PDF, 306 KB

english, 2005

16

Synthesis of Pyrazine Alcaloids from Botryllus leachi. Diazines 43

Buron, Frédéric, Plé,, Nelly, Turck, Alain, Queguiner, Guy

Journal:

Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 835 KB

english, 2005

17

Diazines 13: Metalation without Ortho-Directing Group - Functionalization of Diazines via Direct Metalation

Ple, Nelly, Turck, Alain, Couture, Karine, Queguiner, Guy

Journal:

Journal of Organic Chemistry

Year:

1995

Language:

english

File:

PDF, 802 KB

english, 1995

18

Preparation of Highly Functionalized Pyridylmagnesium Reagents for the Synthesis of Polyfunctional Pyridines

Bérillon, Laurent, Leprêtre, Anne, Turck, Alain, Plé, Nelly, Quéguiner, Guy, Cahiez, Gérard, Knochel, Paul

Journal:

Year:

1998

Language:

english

File:

PDF, 41 KB

english, 1998

19

Regioselective Synthesis and Metalation of Tributylstannylfluoropyrazines. Application to the Synthesis of Some New Fluorinated Liquid Crystals Diazines. Part 34.

Frederic Toudic, Arnault Heynderickx, Nelly Ple, Alain Turck, Guy Queguiner

Journal:

Year:

2003

File:

PDF, 166 KB

2003

20

Syntheses of N-diazinyl thiocarboxamides and of thiazolodiazines. Metalation studies. Diazines XXXIII

Corinne Fruit, Alain Turck, Nelly Plé, Guy Quéguiner

Journal:

Journal of Heterocyclic Chemistry

Year:

2002

Language:

english

File:

PDF, 82 KB

english, 2002

21

Regioselective synthesis and metallation of tributylstannylfluoropyrazines. Application to the synthesis of some new fluorinated liquid crystals diazines. Part 34

Frédéric Toudic, Arnault Heynderickx, Nelly Plé, Alain Turck, Guy Quéguiner

Journal:

Year:

2003

Language:

english

File:

PDF, 257 KB

english, 2003

22

Solid-Phase Syntheses of 6-Arylpyridazin-3( 2H )-Ones

Salives, Richard, Dupas, Georges, Plé,, Nelly, Quéguiner, Guy, Turck, Alain, George, Pascal, Sevrin, Mireille, Frost, Jonathan, Almario, Antonio, Li, Adrien

Journal:

Journal of Combinatorial Chemistry

Year:

2005

Language:

english

File:

PDF, 156 KB

english, 2005

23

Synthesis of 4,5-Diarylquinazolines: A System with Cofacial Aromatic Rings. Diazines. Part 39.

Alexandrine Busch, Valerie Gautheron-Chapoulaud, Jerome Audoux, Nelly Ple, Alain Turck

Journal:

Year:

2004

File:

PDF, 42 KB

2004

24

ChemInform Abstract: Incorporation of Pyridazine Rings in the Structure of Functionalized π-Conjugated Materials.

Sylvain Achelle, Nelly Ple, Alain Turck

Journal:

Year:

2012

File:

PDF, 19 KB

2012

25

Influence of the hydrolysis process on the biological activities of protein hydrolysates from cod (Gadus morhua) muscle

Rozenn Ravallec-Plé, Laura Gilmartin, Alain Van Wormhoudt, Yves Le Gal

Journal:

Journal of the Science of Food and Agriculture

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

26

Synthesis of Pyrazine Alkaloids (I) from Botryllus leachi

Frederic Buron, Nelly Ple, Alain Turck, Guy Queguiner

Journal:

Year:

2005

File:

PDF, 12 KB

2005

27

Syntheses of Sulfoxide Derivatives in the Benzodiazine Series. Diazines. Part 37.

Nicolas Le Fur, Ljubica Mojovic, Alain Turck, Nelly Ple, Guy Queguiner, Vincent Reboul, Stephane Perrio, Patrick Metzner

Journal:

Year:

2004

File:

PDF, 33 KB

2004

28

Relative ortho-directing power of fluorine, chlorine and methoxy group for the metalation reaction in the diazine series. Diazines XXXV

Frédéric Toudic, Alain Turck, Nelly Plé, Guy Quéguiner, Mircea Darabantu, Thierry Lequeux, Jean Claude Pommelet

Journal:

Journal of Heterocyclic Chemistry

Year:

2003

Language:

english

File:

PDF, 75 KB

english, 2003

29

Syntheses and metalation of pyridazinecarboxamides and thiocarboxamides. Diazines. Part 32

Corinne Fruit, Alain Turck, Nelly Plé, Ljubica Mojovic, Guy Quéguiner

Journal:

Year:

2002

Language:

english

File:

PDF, 205 KB

english, 2002

30

Secretagogue activities in cod (Gadus morhua) and shrimp (Penaeus aztecus) extracts and alcalase hydrolysates determined in AR4-2J pancreatic tumour cells

Rozenn Ravallec-Plé, Alain Van Wormhoudt

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 950 KB

english, 2003

31

ChemInform Abstract: The Proton Sponge—Triethylamine Tris(hydrogen fluoride) System as a Selective Nucleophilic Fluorinating Reagent for Chlorodiazines.

Mircea Darabantu, Thierry Lequeux, Jean-Claude Pommelet, Nelly Ple, Alain Turck, Loic Toupet

Journal:

Year:

2000

File:

PDF, 32 KB

2000

32

First functionalization by metallation of the benzene moiety of quinazolines. Diazines XIX

Nelly Plé, Alain Turck, Valérie Chapoulaud, Guy Quéguiner

Journal:

Year:

1997

Language:

english

File:

PDF, 1.08 MB

english, 1997

33

FIRST EXAMPLES OF THE CONFORMATION CHIRALITY OF HETEROBICYCLO[3.3.0]OCTANES : 3,7-DIOXA-r-1-AZABICYCLO[3.3.0]OCT-c-5-YL-METHOXYPYRAZINES

Berghian, Camelia, Darabantu, Mircea, Lameiras, Pedro, Plé, Nelly, Turck, Alain

Journal:

Heterocyclic Communications

Year:

2005

Language:

english

File:

PDF, 1.22 MB

english, 2005

34

Ibrutinib brain distribution: a preclinical study

Goldwirt, Lauriane, Beccaria, Kevin, Ple, Alain, Sauvageon, Hélène, Mourah, Samia

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2018

Language:

english

File:

PDF, 873 KB

english, 2018

35

Development and Validation of A Simultaneous Quantification Method of Ruxolitinib, Vismodegib, Olaparib, and Pazopanib in Human Plasma Using Lc-Ms/Ms

Pressiat, Claire, Huynh, Huu-Hien, Plé, Alain, Sauvageon, Hélène, Madelaine, Isabelle, Chougnet, Cécile, Le Maignan, Christine, Mourah, Samia, Goldwirt, Lauriane

Journal:

Therapeutic Drug Monitoring

Year:

2018

Language:

english

File:

PDF, 774 KB

english, 2018

36

Metalation of Sulfoxides in the Benzodiazine Series. Diazines. Part 44.

Nicolas Le Fur, Ljubica Mojovic, Nelly Ple, Alain Turck, Francis Marsais

Journal:

Year:

2005

File:

PDF, 28 KB

2005

37

ortho -Metalation of Enantiopure Aromatic Sulfoxides and Stereocontrolled Addition to Imines

Le Fur, Nicolas, Mojovic, Ljubica, Plé, Nelly, Turck, Alain, Reboul, Vincent, Metzner, Patrick

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 153 KB

english, 2006

38

Synthesis of new flat polyheterocyclic systems potential DNA intercalating agents diazines part 47

Jérôme Audoux, Sylvain Achelle, Alain Turck, Francis Marsais, Nelly Plé

Journal:

Journal of Heterocyclic Chemistry

Year:

2006

Language:

english

File:

PDF, 345 KB

english, 2006

39

First functionalization by metallation of the pyridine moiety of pyridopyrimidin-4(3H)-ones. Diazines. Part 36

Jérôme Audoux, Nelly Plé, Alain Turck, Guy Quéguiner

Journal:

Year:

2004

Language:

english

File:

PDF, 490 KB

english, 2004

40

A New Route to Aminodiazines via Metalation Reaction. Synthesis of an Aza Analogue of Nevirapine: Diazines XV

Plé, Nelly, Turck, Alain, Couture, Karine, Quéguiner, Guy

Journal:

Year:

1996

File:

PDF, 516 KB

1996

41

Selective Thiophilic Addition of Alkyl- and Aryllithiums to Dithio Esters and a Sulfine in the Pyridine Series

Metzner, Patrick, Lempereur, Claude, Plé, Nelly, Turck, Alain, Quéguiner, Guy, Corbin, Florence, Alayrac, Carole

Journal:

Year:

1998

Language:

english

File:

PDF, 610 KB

english, 1998

42

ChemInform Abstract: Preparation of Highly Functionalized Pyridylmagnesium Reagents for the Synthesis of Polyfunctional Pyridines.

Laurent Berillon, Anne Lepretre, Alain Turck, Nelly Ple, Guy Queguiner, Gerard Cahiez, Paul Knochel

Journal:

Year:

1999

File:

PDF, 26 KB

1999

43

Connection Between Metalation of Azines and Diazines and Cross-Coupling Startegies for the Synthesis of Natural and Biologically Active Molecules

Quéguiner, Guy, Godard, Alain, Marsais, Francis, Plé, Nelly, Trécourt, François, Turck, Alain

Journal:

Year:

1995

Language:

english

File:

PDF, 647 KB

english, 1995

44

ChemInform Abstract: Organozinc Derivatives of Diazines, Metalation of Diazines. Part 23.

Alain Turck, Nelly Ple, Anne Lepretre-Gaquere, Guy Queguiner

Journal:

Year:

1999

File:

PDF, 34 KB

1999

45

Chemistry of 1,2,4-triazines, XV. First metalation of 1,2,4-triazine derivatives

Nelly Plé, Alain Turck, Guy Quéguiner, Bernd Glassl, Hans Neunhoeffer

Journal:

European Journal of Organic Chemistry

Year:

1993

Language:

english

File:

PDF, 294 KB

english, 1993

46

ChemInform Abstract: Syntheses in the Nitrogen π-Deficient Heterocycles Series Using a Barbier-Type Reaction under Sonication. Diazines. Part 29.

Anne Lepretre, Alain Turck, Nelly Ple, Guy Queguiner

Journal:

Year:

2000

File:

PDF, 34 KB

2000

47

Aryl-aryl bonds formation in pyridine and diazine series. Diazines part 41

Ludovic Boully, Alain Turck, Nelly Plé, Mircea Darabantu

Journal:

Journal of Heterocyclic Chemistry

Year:

2005

Language:

english

File:

PDF, 169 KB

english, 2005

48

Synthesis of 4,5-diarylquinazolines: a system with cofacial aromatic rings. Diazines. Part 39

Alexandrine Busch, Valérie Gautheron Chapoulaud, Jérôme Audoux, Nelly Plé, Alain Turck

Journal:

Year:

2004

Language:

english

File:

PDF, 426 KB

english, 2004

49

On the metalation of 3-substituted and 3,6-disubstituted pyridazines

Alain Turck, Nelly Plé, Bruno Ndzi, Guy Quéguiner, Norbert Haider, Herbert Schuller, Gottfried Heinisch

Journal:

Year:

1993

Language:

english

File:

PDF, 650 KB

english, 1993

50

Oligomers Containing Ethynylpyridazine Moieties: Synthesis, Fluorescence and Liquid Crystalline Properties. Diazines 50

Plé, Nelly, Achelle, Sylvain, Kreher, David, Mathevet, Fabrice, Turck, Alain

Journal:

Year:

2008

Language:

english

File:

PDF, 285 KB

english, 2008

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